Chemical Industry Weekly News Round-Up, June 8
This Week on CW: At ACC’s 2012 annual meeting in Colorado Springs, CO, industry leaders expressed growing concern about declining energy and chemical prices and inventory destocking. Five major multinationals, including Coca-Cola, have formed a...Unipetrol Closes Unprofitable Urea Plant
Unipetrol (Prague), a member of the PKN Orlen Group (Plock, Poland), said today that it intends to close permanently its urea production facility at Litvínov, Czech Republic by the end of this year. The company cites economic reasons for the closure...Rockwood-Kemira TiO2 JV Refinances Debt
Sachtleben (Duisburg, Germany), Rockwood and Kemira’s titanium dioxide (TiO2) joint venture, has entered into a new €430 million ($540 million) credit agreement consisting of two term loans and a revolving credit line, all of which mature in 2017. The term...Tessenderlo to Build Specialty Fertilizers Plant in California
Tessenderlo Kerley Inc. (TKI; Phoenix, AZ), a Tessenderlo Group subsidiary, has announced plans to build a thiosulfate fertilizers plant at Hanford, CA. The company says it will also "optimize" its Fresno, CA facility to...Westlake Divides Olefins and Business Development Units
Westlake Chemical says it has split its olefins and business development unit into two separate departments in order to provide focused attention and resources to the company’s ongoing corporate business development...Dow Corning Opens Distribution Center in Belgium
Dow Corning says it has opened a 344,445-sq feet energy-efficient distribution center at Feluy, Belgium. The new distribution center more than doubles the capacity of Dow Corning's previous warehouse in Europe, and it cost more than €30 million, the...Ethylene Falls to Near 10-Year Low
U.S. ethylene contracts for the month of May have settled at a decrease of 9 cts/lb, to 46.25 cts/lb, on lower spot prices and reduced production costs. The settlement reflects a 16% decrease from April levels and...Coca-Cola Joins with Four Multinationals in Push for Biobased PET
Coca-Cola, Ford Motor Company, H.J. Heinz, Nike and Procter & Gamble have formed a consortium to promote research for developing polyethylene terephthalate (PET) that is 100% derived from renewable raw materials, a move that executives say will extend...Bayer Completes Global Switch in Chlorine Production to Membrane Technology, Advances ODC Process
Bayer MaterialScience says it has completed a global switch in chlorine production to electricity-saving membrane technology. In addition, Bayer is also at the halfway point of a test phase for another pioneering process - known as the oxygen depolarized...
Activities in Japan) Recent Major Achievements (Activities overseas - focusing on environmental, health and safety issues)
Advocates chemical industry views, opinions, and policy recommendations to regulatory authorities.
Presents policy proposals and recommendations to other related parties.
Sits on or recommends individuals who should sit on government advisory councils and expert committees.
Communicates regulatory news and information to JCIA members.
1. Provided industry opinions in the government review of the regulations on chemical substances, the environment, and occupational health and safety.
2. Provided position papers in the proposed revision of Commercial Code and tax laws.
3. Provided opinions on various themes suche as climate change in the government advisory councils like industrial Structure Council and Central Environmental Council.
4. Worked on environmental and quality control standards, and promoted standardizing initiatives such as chemical laboratory accreditation system, including necessary education and training.
5. Continued to provide relevant information to e-mail news networks with elements such as "JCIA EHS Net", "REACH Net", "Trade Net", "Japan-China Net", "Finance & Economy net" and "PR Net" to members.
Participates in ICCA initiatives for the assessment of chemicals and promotes joint voluntary research initiatives as well as activities relating to Energy adn Climate Change Leadership Group (Japan is the chair country of the group).
Participates in various international conferences to present JCIA views and recommendations, and promotes information exchanges with the chemical industries of the United States, Europe and other parts of the world.
Works to achieve global harmonization of standards relating to the environment, health and safety.
Recent Major Achievements
1. Parricepate in ICCA voluntary activities relating to the management of chemicals including ICCA High Production Volume (HPV) Initiative (hazard assessment of high production volume chemical products).
2. Participated in ICCA Long-range Research Initiative (LRI): industry's voluntary and long-range research program on the safety of chemical products.
3. Response to SAICM: Strategic Approach to International Chemical Management.
4. Registration, Evaluation, Authorization of Chemicals (REACH): addressing the proposed new European regulations on chemical products.
5. Participated in activities relating to the management of chemicals organized by OECD and other bodies.
6. Worked for the Globally Harmonized System for the Classification and Labeling of Chemicals (GHS).
7. Promoted worldwide activities to cope with global warming issues as the leader and chair coutry of the ICCA Energy and Climate Change Leadership Group.
With the Copenhagen negotiations on climate change now underway, the European chemical industry wishes to reaffirm its support to their successful conclusion as a prerequisite to bring the global economy onto a path towards the desired global emission reductions. Some effective (efficient) international agreements must be made in that respect.
A successful, truly international agreement must:
- promote new climate friendly technologies
- disseminate climate friendly tools
- support responsible behaviours
The European chemical industry can contribute the decisive bricks and mortar to build such an international framework by enabling or providing concrete solutions.
1. An effective (efficient) agreement must promote the development of new climate friendly technologies
If they are to comply with current requirements from United Nations bodies limiting the global temperature increase to 2°C, the world’s economies must disseminate more technologies that save more greenhouse gas (GHG) emissions. This requires even newer innovative technologies for increased savings compatible with growing populations and modern needs. Many countries are developing low carbon transition plans to guide long- term global GHG reductions. They need such tools.
This need for innovation and investment implies the promotion of a highly competitive European chemical industry given its carbon abatement capacities and the importance of its downstream users. The EU chemical industry is an important contributor to socio-economic development. It comprises 27,000 companies, employing directly 1.2 million people and generating a trade surplus of 35.4 billion Euros in 2007.
Avoid unfair competition
This competitiveness requires a truly international agreement to avoid detrimental unfair competition. As long as important emerging economies do not make binding commitments, the value of the industrialised nations’ commitments - in terms of the global abatement effect - will not stop dangerous climate change as the International Energy Agency (IEA) and (Intergovernmental Panel on Climate Change (IPCC) show. Persisting global climate policy imbalances may lead to relocation of manufacturing to regions with a carbon-intensive energy mix, thereby accelerating global carbon emissions (=“carbon leakage”) even further.
Carbon leakage is to be avoided, by an effective international agreement where all nations commit to comparable greenhouse gas reductions. Such reductions are possible via the dissemination of efficient tools, mainly provided by the chemical industry (like insulation, modern plastics, new lighting, renewables….). Outside the EU, other industrialised countries are also making economy-wide emission reduction commitments. This development is greatly appreciated by the EU chemical industries as this will hopefully bring the global economy onto a path towards the desired global emission reductions and eventually reduce the competitive disadvantage for ‘early movers’ (=industries already operating under carbon constraint regimes).
2. An effective agreement must promote the dissemination of innovative climate products and technologies from the chemical industry throughout the world’s economies
Innovative solutions must be globally disseminated to reduce greenhouse gas emissions wherever there are consumers. National and global frameworks have to focus on the largest, most effective and lowest-cost abatement opportunities. These opportunities should be explored based on the full life cycle, not only on emissions during the manufacturing phase of products and activities. Incentives may support substantive adoption of such opportunities.
Protectionist trade policy measures are unacceptable and ineffective for enforcing climate protection targets. A successful climate policy depends on undistorted markets and free and fair trade: the climate solutions cannot remain where they have been created - they must be traded on an international basis. Intellectual Property rights must be protected as they stimulate research and technology deployment.
To ease further dissemination of low carbon tools, flexible mechanisms like CDM (Clean Development Mechanisms) must be reinforced: they provide incentives to business to invest in cost- effective emission reductions within developing countries, enabling technology dissemination.
Have proper climate incentives
Effective (Efficient) climate solutions should be designed to impose proper incentives only so as to drive capital flows to low carbon tools - not to create external markets more concerned by their own profitability than by the emissions reductions efficiency. The auctioning of allowances under the EU Emissions Trading Scheme is under development and must be designed in order to allow operators of installations to have direct access to the required allowances and to achieve emission reductions at the lowest cost. The auctioning share of total EU allowances must not be extended for the purpose of filling gaps for financing international climate protection measures. Instead, these resources are essential for EU companies to further deliver on research, development and low-carbon innovation. Generated revenues must be channelled back to industry to support breakthrough technology enabling climate change mitigation.
3. An effective agreement must promote committed behaviours for a sustainable economy
The European chemical industry is showing constructive commitments and sustainable performances. Between 1990 and 2005, chemical production in the EU rose by 60 percent, while total energy consumption was stable. This means that the chemical industry has cut its energy intensity by 3.6 percent annually. Absolute greenhouse gas emissions, meanwhile, were reduced by almost 30 percent. A global study of 2009 shows further significant minimization potentials outside the EU in emerging economies (see video and news), whilst the domestic potential is limited - often involving disproportionate costs. Such behaviour should be encouraged by the provisions of an international agreement.
The European Union has made legally binding economy-wide commitments (-20% by 2020 compared to 1990) that are being implemented mainly by specific economic sectors through the EU cap and trade system. Such commitments cannot deliver unless other countries commit in comparable directions. Sharing national commitments in an international agreement is in fact responsible - otherwise unfair competition is created and efficient technologies are prevented from being disseminated by companies that have invested heavily. The current EU strategy implies in fact an increasing cost burden on these EU sectors that until now has remained unilateral, thus weakening their international competitiveness. The EU chemical industry feels it is not appropriate for the EU to move in the negotiations at COP15 in Copenhagen to an even higher target putting further constraints on sectors. This would first require a proper in-depth peer-reviewed economic and analysis taking into account other countries commitments and economic effects.
A balanced climate burden for all regions
A responsible behaviour implies a well balanced burden for all regions, economies and sectors. Derived from the principle of "common but differentiated responsibilities" as agreed in the Framework Convention on Climate Change, some parties offer even further significant emission increases for emerging and developing countries. Moreover, concepts such as “sectoral crediting” and “no-lose targets” are being discussed - meant to integrate developing countries, i.e. emerging economies. However, as long as diverse treatment of sectors and companies resulting in no or lower carbon costs in different regions is allowed to continue or worsen, this will enable strong production growth - especially outside of the EU in the chemical industry's main competitor countries of the future (China, India and the Arabic region) - whilst growth perspectives in Europe are already restricted by the existing cap and trade rules. This policy will make the "carbon leakage" problem permanent, requiring effective measures such as performance-based free allocation of emission rights for sectors exposed to climate policy-induced competitive disadvantages.
Cambrex Continuous-Flow Microwave-Assisted Organic Synthesis Technology Nominated for 2009 Innovations Award
News Releas
East Rutherford, NJ., Sept. 16 -- Cambrex Corporation (NYSE: CBM) announced today that its Continuous-Flow Microwave-Assisted Organic Synthesis (CF-MAOS) technology has been accepted as a nominee for the 2009 Innovations Awards at CPhI, an important upcoming pharmaceutical ingredients exhibition to be held in Madrid, Spain.
The CF-MAOS technology represents a dual technological breakthrough, allowing both the scale-up of microwave-assisted chemistry and the handling of heterogeneous mixtures in continuous-flow. This new technology will finally bring the benefits of both technologies out of the laboratory and into production. The CaMWave(TM) KiloLAB flow reactor is capable of manufacturing in excess of 20 kilograms of product per day, and combined with larger reactors, can generate more than one hundred metric tons of product per year. This versatile technology facilitates faster, cleaner, more reliable reactions, leading to improved productivity and lower manufacturing costs.
The technology will be presented during the CPhI Innovation Awards: Title: Microwave Chemistry - Out of the Lab and Into ProductionSpeaker: Dr. Jayne E. MuirDate: October 13, 2009Location: Hall 10, Stand 10G16Time: 11:00-11:20 a.m.Visit Cambrex at CPhI in Madrid at Feria de Madrid Hall 3, Stand 3C70 on October 13-15, 2009.
About Cambrex
Cambrex provides products and services to accelerate the development and commercialization of small molecule therapeutics including active pharmaceutical ingredients ("API"), advanced intermediates, enhanced drug delivery, and other products for branded and generic pharmaceuticals. For more information, please visit Stephanie LaFiura
SOURCE:ir.cambrex.com/phoenix.zhtml?c=80683&p=irol-newsArticle&ID=1332730
Tradeshows-biz.com presents one and only information bank for all kinds of details related to chemical tradeshows. Chemical is an immensely used material with incalculable applications. Chemical is an indispensably used material in everyday life. We might not realize but in direct or indirect way, we all use chemical in routine life. The huge consumption of chemicals has boosted the entrepreneurs dealing in chemical industry. Increasing demand and innovations in chemical industry has also amplified the arrangement of chemical tradeshows. Chem expos, Petrochemical trade events, Fertilizer exhibitions etc., are happening more repeatedly than ever. Worldwide occurrence of chemical tradeshows is being more frequent and organized as well. Tradeshows-biz.com has apprehend this trend and quipped itself with complete details of global chemical tradeshows. Here you may browse for all kind of details for chemical tradeshows happening in nook and corner of globe. By clicking on this segment you may get any and every information about venue, schedule, organizer etc., of chemical tradeshows happening across the seas.
SOURCE:tradeshows-biz.com/chemicals/
Trade Shows Name
Start / End Date
Country
O&S
03-Jun-2009 To 05-Jun-2009
Germany
Asia Pacific Coatings Show
03-Jun-2009 To 05-Jun-2009
Malaysia
Seed Agrochem & Irrigation Expo
05-Jun-2009 To 07-Jun-2009
India
ICHEAP & PRES
10-Jun-2009 To 13-Jun-2009
Italy
Escape
14-Jun-2009 To 17-Jun-2009
Poland
Trade Shows Name
Start / End Date
Country
O&S
03-Jun-2009 To 05-Jun-2009
Germany
Asia Pacific Coatings Show
03-Jun-2009 To 05-Jun-2009
Malaysia
Seed Agrochem & Irrigation Expo
05-Jun-2009 To 07-Jun-2009
India
ICHEAP & PRES
10-Jun-2009 To 13-Jun-2009
Italy
Escape
14-Jun-2009 To 17-Jun-2009
Poland
founded in 1997, is the main man-ufacturer of bromide series in China, 5000 tons of bromide series are produced ann-ually in our factory, which are salable in China, and long exported to North America, Europe, Japan, India, Southeast Asia, Taiwan district, and etc. Best quality with reaso-nable price is our tenet to satisfy all our clients.
Our factory was prepared with perfect basic facilities, advanced creative technics, co-mplete test instruments, and in order to protect the environment, we insist on dealing with the three industrial waste, exhaust gas, waste water and the waste residue, which let out up to par.
Our factory was first passed through the ISO9001 international quality system attestation in 2000, and we organize the manufacturing and work the managing strictly complying with the demand.We make hard work to insure the quality superexcel-
lent at home, and on top over the world.
The technic potence is powerful, there are more than ten chemical professionals in our factory, one doctor and two masters are among them. The resource of technic is extensive, we have established permanent cooperative relationship with pharmaceutical institute of Beijing university and Shanghai organic graduate school. In order to satisfy the requirement in market, the center of Long
shen technic research which founded in July, 2000, insistently improves on creative technics and excogitates new products .
SOURCE: longshenchem.com/template/aboute.htm
chemical equilibrium state of balance in which two opposing reversible chemical reactions proceed at constant equal rates with no net change in the system. For example, when hydrogen gas, H 2 , and iodine gas, I 2 , are mixed, and gaseous hydrogen iodide, HI, is formed according to the equation H 2 + I 2 → 2HI, no matter how long the reaction is allowed to proceed some quantity of hydrogen and iodine will remain unreacted. The reason reactants in a reversible reaction are never completely converted to product is that an opposing reaction is taking place simultaneously, i.e., some of the newly formed HI is being converted back into hydrogen and iodine. For any particular temperature, a point of equilibrium is reached at which the rates of the two opposing reactions are equal and there is no further change in the system. This equilibrium point is characterized by specific relative concentrations of reactants and products and will also be reached from the opposite direction, i.e., if one starts with hydrogen iodide and allows it to decompose into hydrogen and iodine. The equilibrium point can be described by the mass action expression, which defines the equilibrium constant, Keq , in terms of the ratio of the molar concentrations of the products to those of the reactants. For the reversible reaction used as an example, the equilibrium constant is Keq =[HI] 2 /[H 2 ][I 2 ]; for the general reversible reaction n A + m B + · · · [double arrow] p C + q D + · · · , the equilibrium constant is: where [A], [B], [C], [D], … are the molar concentrations of the substances and n, m, p, q, … are the coefficients of the balanced chemical equation. The larger the equilibrium constant for a given reaction, the more the reaction is favored, since a larger value of Keq means larger concentrations of the products relative to the reactants. The equilibrium constant is related to the change in the standard free energy, G °, of the system by the equation Δ G ° = - RT. ln Keq , where R is a constant, T is the temperature in degrees Kelvin, and ln Keq is the natural logarithm of the equilibrium constant. Chemical equilibrium can be defined for many types of chemical processes, such as dissociation of a weak acid in solution, solubility of slightly soluble salts, and oxidation-reduction reactions. In all of these cases, the equilibrium constant or its analogue is defined for certain conditions of temperature and other factors. If any of these factors change, the system will respond to establish a new equilibrium,
source:
encyclopedia.com/topic/chemical_equilibrium.aspx
Normally, your cells grow and die in a controlled way. Cancer cells keep forming without control. Chemotherapy is drug therapy that can stop these cells from multiplying. However, it can also harm healthy cells, which causes side effects.
During chemotherapy you may have no side effects or just a few. The kinds of side effects you have depend on the type and dose of chemotherapy you get. Side effects vary, but common ones are nausea, vomiting, tiredness, pain and hair loss. Healthy cells usually recover after chemotherapy, so most side effects gradually go away.
Your course of therapy will depend on the cancer type, the chemotherapy drugs used, the treatment goal and how your body responds. You may get treatment every day, every week or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs by mouth, in a shot or intravenously.
Chemical oxygen demand (COD) is a measure of the capacity of water to consume oxygen during the decomposition of organic matter and the oxidation of inorganic chemicals such as ammonia and nitrite. COD measurements are commonly made on samples of waste waters or of natural waters contaminated by domestic or industrial wastes. Chemical oxygen demand is measured as a standardized laboratory assay in which a closed water sample is incubated with a strong chemical oxidant under specific conditions of temperature and for a particular period of time. A commonly used oxidant in COD assays is potassium dichromate (K2Cr2O7) which is used in combination with boiling sulfuric acid (H2SO4). Because this chemical oxidant is not specific to oxygen-consuming chemicals that are organic or inorganic, both of these sources of oxygen demand are measured in a COD assay.
Chemical oxygen demand is related to biochemical oxygen demand (BOD), another standard test for assaying the oxygen-demanding strength of waste waters. However, biochemicaloxygen demand only measures the amount of oxygen consumed by microbial oxidation and is most relevant to waters rich in organic matter. It is important to understand that COD and BOD do not necessarily measure the same types of oxygen consumption. For example, COD does not measure the oxygen-consuming potential associated with certain dissolved organic compounds such as acetate. However, acetate can be metabolized by microorganisms and would therefore be detected in an assay of BOD. In contrast, the oxygen-consuming potential of cellulose is not measured during a short-term BOD assay, but it is measured during a COD test.
The chemical reaction campaign has come to an end now that the new European Chemicals law, REACH, has come into force.
However, now the law is in place there is much to be done to ensure that it really does protect us from the worst chemicals; the following web sites can tell you more about what is happening now.
- ChemTrust
- Greenpeace
- Chemicals Health Monitor Project
- International Chemicals Secretariat
- The "substitute it now" campaign against the worst chemicals
- WWF
Read a presentation about the implementation of REACH here
Following an almost nine year long discussion on the European Chemicals policy reform, the new law, REACH, was finally approved on 18 December 2006. REACH, which stands for Registration, Evaluation and Authorisation of Chemicals, is a first modest step by the European Union towards a new approach to chemicals management. It� promises to put an end to public ignorance about the health and environmental effects of chemicals, many of them incorporated in everyday products, and phase out the most hazardous chemicals from the market if safer alternatives are available (the substitution principle).
Under REACH, companies will have to provide safety data for large volume chemicals that they produce or import into Europe, while the use of most dangerous ones (such as the ones causing cancer, infertilities or that persist in our bodies or the environment) will have to be authorized by the European Commission.
REACH will cover 30,000 of the 100,000 chemicals available on the EU market and came into force in June 2007. As a regulation, it will have direct effect in all 27 member states as well as on chemicals and articled imported into the EU.
Unfortunately, REACH also contains many loopholes which will still allow many hazardous chemicals to continue being used in manufacturing and consumer goods. Additional concessions exempt companies which import and manufacture chemicals in volumes below 10 tonnes a year - 60% of chemicals covered by REACH - from the requirement to provide any meaningful safety data. Moreover, many decisions have been postponed to the implementation and future revisions of the law. See timeline
Will REACH deliver?
The loopholes and provisions for self-regulation contained in the law leave REACH very vulnerable to further manipulation by the chemical industry. There remains plenty of room for the chemical industry to manoeuvre around the loopholes to keep hazardous substances on the market, even if safer alternatives exist. The new EU Chemicals Agency in Helsinki will have to be closely monitored to ensure that REACH can deliver. Without the necessary support, hazardous chemicals will continue to contaminate wildlife, our homes and our bodies, and REACH will prove a failure.
This is why in the future we will need to keep careful watch over how the law is put into practice and to ensure that it delivers promised benefits to human health and environment. We will keep informing you on how you can press for change and use REACH to ensure better protection from toxic chemicals for you, your family and your environment.

Pretty much anything you buy - whether it's soap or a computer, perfume or paints - will contain a mixture of substances produced in a chemical factory. Chemicals are used for all kinds of reasons such as to smell nice or to kill germs.
The uncomfortable truth is, more and more research is suggesting that some chemicals are threatening our health with a new kind of pollution that contaminates the bodies of us and our families
Dichromate Reflux Technique Standard Method.
Equipment Required
- 500-millilitre (ml) Erlenmeyer flask with standard (24/40) tapered glass joints
- Friedrichs reflux condensers (12-inch) with standard (24/40) tapered glass joints
- Electric hot plate or six-unit heating shelf
- Volumetric pipettes (10, 25, and 50ml capacity)
- Burette, 50 ml - 0.1 ml accuracy
- Burette stand and clamp
- Analytical balance, accuracy 0.001gram (g)
- Spatula
- Volumetric flasks (1,000ml capacity)
- Boiling beads, glass
- Magnetic stirrer and stirring bars
Chemicals Required
- Potassium dichromate (K2Cr2O7) 0.25N
- Sulphuric acid (H2SO4) / silver sulphate (Ag2SO4) solution
- Mercuric sulphate (HgSO4) crystals
- Ferrous ammonium sulphate (FAS) [Fe(NH4)2(SO4)2], approximately 0.01N
- Ferroin indicator (1, 10-phenanthroline and ferrous ammonium sulphate)
Caution: In carrying out the following procedures, use proper safety measures, including protective clothing, eye protection, and a fume hood. Reagents containing heavy metals (HgSO4 and Ag2SO4) should be disposed of as toxic wastes.
Chemical Preparation
- Dissolve 12.259g of oven-dried (primary standard grade dried at 103oC to a constant weight) potassium dichromate in distilled water and dilute to 1 litre volume in a volumetric flask.
- Add 22g of reagent grade silver sulphate to a 4kg bottle of concentrated sulphuric acid (H2SO4) and mix until the silver sulphate goes into solution.
- Use 1 g of mercuric sulphate (HgSO4) to complex 100 mg chloride (2,000 mg/l).
- Dissolve 1.485g of 1,10-phenanthroline monohydrate and 0.695g of ferrous ammonium sulphate heptahydrate in distilled water and dilute to approximately 100ml. (Alternatively, this indicator may be purchased as Ferroin Indicator from most scientific suppliers.)
- Dissolve 39g reagent grade ferrous ammonium sulphate hexahydrate in distilled water. Add 20ml of concentrated sulphuric acid (H2SO4). Cool and dilute to exactly 1 litre in a volumetric flask using distilled water. The ferrous ammonium sulfate (FAS) titrant must be standardized daily by the following procedure:
Dilute 10ml of standard potassium dichromate (K2Cr2O7) solution to 100ml with distilled water. Slowly add 30ml of concentrated sulphuric acid and cool to room temperature. Titrate with ferrous ammonium sulphate titrant, using 2 to 3 drops (0.10 to 0.15 ml) of Ferroin indicator.
Normality of FAS = (ml K2Cr2O7)(0.25)
ml FAS requiredThe deterioration of FAS can be decreased if it is stored in a dark bottle.
Procedure
- Place a 50ml sample or an aliquot diluted to 50ml in a 500ml refluxing flask. The blank is prepared using 50ml of distilled water. This is a precise measurement and a 50ml volumetric pipette should be used. Refer to COD Range
- Add 5 to 7 glass boiling beads.
- Add 1g of mercuric sulphate (HgSO4), 5ml of concentrated sulphuric acid / silver sulphate solution, and mix until the HgSO4 is in solution. The function of the mercuric sulphate is to bind or complex chlorides. One gram may not be required if the chloride concentration is low. (Caution: Always add acid slowly down the side of the flask while mixing to avoid overheating. It may be necessary to use gloves because of the heat generated.)
- Accurately add 25ml of 0.25 N potassium dichromate (K2Cr2O7) and mix.
- Add while mixing, an additional 70ml of concentrated sulphuric acid-silver sulphate solution.
- After thorough mixing, attach the flask to the reflux condenser, apply heat, and reflux for 2 hours. Refluxing time can be decreased depending on the ease of oxidation of organic materials. This time may be determined by refluxing for periods from 15 minutes to 2 hours and comparing the results.
- A reagent blank containing 50ml of distilled water treated with the same reagent as the sample should be refluxed with each set of samples.
- Cool the apparatus to room temperature after the refluxing period. Wash down the interior of the condenser and flask twice with approximately 25ml portions of distilled water.
- Remove flask from the condenser and dilute to a final volume of approximately 350ml with distilled water.
- Add 4 to 5 drops of Ferroin indicator and a magnetic stirring bar.
- Place flask on a magnetic stirrer and rapidly titrate with 0.1 N ferrous ammonium sulphate to the first red-brown endpoint.
Caution: Use care in titration. The endpoint is very sharp and may be reached rapidly.
Formula to determine COD:
COD (mg/l) = (a-b)(N) x 8,000 / sample size (ml)
Where:
a = ml Fe(NH4)2(SO4)2 used for blank
b = ml Fe(NH4)2(SO4)2 used for sample
N = normality of FAS titrant (Fe(NH4)2(SO4)2)
ml sample = the actual volume of sample used before dilution
Sources of Error
COD Range and Sample Size
COD Range (mg/l) 50-800 100-1500 240-3700 480-7500 1200-18800 2400-3700 40000-375000 Volume of Sample (ml) 50 25 10 5 2 1 0.1 All samples high in solids should be blended for 2 minutes at high speed and stirred when an aliquot is taken. Sample volumes less than 25ml should not be pipetted directly, but serially diluted and then a portion of the diluent removed:
Elimination of Interference
One gram of mercuric sulphate (HgSO4) will complex 100mg of chloride in a 50ml sample (2,000 mg/l). For samples higher in chloride more HgSO4 should be used in the ratio of 10:1 HgSO4.
Interference from nitrites can be prevented by the addition of 10:1 ratio of sulfamic acid:nitrite. The addition of the silver sulphate (AgSO4) concentrated sulphuric acid (H2SO4) refluxing acid will aid in the oxidation of some organic nitrogen compounds, but aromatic hydrocarbons and pyridine are not oxidized to any appreciable amount.
To visualize a synthesis reaction look at the cartoon
Chemical changes are a result of chemical reactions. All chemical reactions involve a change in substances and a change in energy. Neither matter or energy is created or destroyed in a chemical reaction---only changed. There are so many chemical reactions that it is helpful to classify them into 4 general types which include the following: SYNTHESIS REACTION
In a synthesis reaction two or more simple substances combine to form a more complex substance. Two or more reactants yielding one product is another way to identify a synthesis reaction.
For example, simple hydrogen gas combined with simple oxygen gas can produce a more complex substance-----water!
The chemical equation for this synthesis reaction looks like:
reactant + reactant -------> product
SOURCE;usoe.k12.ut.us/CURR/Science/sciber00/8th/matter/sciber/chemtype

Cigarettes are one of few products which can be sold legally which can harm and even kill you over time if used as intended.
Currently there are ongoing lawsuits in the USA which aim to hold tobacco companies responsible for the effects of smoking on the health of long term smokers.
Benzene (petrol additive)
A colourless cyclic hydrocarbon obtained from coal and petroleum, used as a solvent in fuel and in chemical manufacture - and contained in cigarette smoke. It is a known carcinogen and is associated with leukaemia.
Formaldehyde (embalming fluid)
A colourless liquid, highly poisonous, used to preserve dead bodies - also found in cigarette smoke. Known to cause cancer, respiratory, skin and gastrointestinal problems.
Ammonia (toilet cleaner)
Used as a flavouring, frees nicotine from tobacco turning it into a gas, found in dry cleaning fluids.
Acetone (nail polish remover)
Fragrant volatile liquid ketone, used as a solvent, for example, nail polish remover - found in cigarette smoke.
Tar
Particulate matter drawn into lungs when you inhale on a lighted cigarette. Once inhaled, smoke condenses and about 70 per cent of the tar in the smoke is deposited in the smoker's lungs.
Nicotine (insecticide/addictive drug)
One of the most addictive substances known to man, a powerful and fast-acting medical and non-medical poison. This is the chemical which causes addiction.
Carbon Monoxide (CO) (car exhaust fumes)
An odourless, tasteless and poisonous gas, rapidly fatal in large amounts - it's the same gas that comes out of car exhausts and is the main gas in cigarette smoke, formed when the cigarette is lit. Others you may recognize are :
Arsenic (rat poison), Hydrogen Cyanide (gas chamber poison)
source: Health Education Authority (UK) - Lifesaver
SOURCE;quit-smoking-stop.com/harmful-chemicals-in-cigarettes

Chromatex chemicals has been the textile industry's expert partner in the field of textile chemicals for many years. Our concepts for pretreatment,dyeing auxiliaries, finishing and textile printing offer high-quality chemicals for textile processing. We are one of the world's top international companies. With our Chroma® & Dura® brands for cellulosic fibres and its blends with polyester, we lead the world in textile chemicals.
Innovative solutions to problems are our speciality - a decided competitive advantage for our customers. A few examples: pH controllers for finished textiles, eco-efficient peroxide killers, multipurpose detergents and product packages for shorter pretreatment and dyeing processes. As a competitive partner to the textile industry, we have marketing companies in most countries of the world. In addition, we can provide the technical services and production sites across the globe.
CHROMA GARNET ABRASSIVES are high quality natural abrasives. Natural garnet grains and powder of all sizes are cost effective, alternative for silica sand, mineral slags and steel grits because of low consumption (kg/m2) and high productivity (m2/hr).
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UNEP Chemicals Branch
The Chemicals Branch works towards making the world a safer place from toxic chemicals by helping governments take needed global actions for the sound management of chemicals, by promoting the exchange of information on chemicals, and by helping to build the capacities of countries around the world to use chemicals safely.
Persistent Organic Pollutants (POPS)
POPs are chemicals that persist, bioaccumulate in plants and animals, are transported long distances in the environment, and are toxic to people. The UNEP Chemicals Branch work on POPs facilitates the negotiations of a legally binding international instrument on POPs and promotes the early reduction and elimination of releases of POPs into the environment through information exchange and capacity building programmes.
OzonAction Branch
Under the Montreal Protocol on Substances that Deplete the Ozone Layer, countries worldwide are taking specific, time-targeted actions to reduce and eliminate the production and consumption of man-made chemicals that destroy the stratospheric ozone layer, Earth’s protective shield.
GEF Reduction of Persistent Organic Pollutants
In May 2001, governments adopted the Stockholm Convention on Persistent Organic Pollutants (POPs) and named the GEF as the Convention's interim financial mechanism, pending entry into force of the Convention. In October 2002, the GEF Assembly approved the addition of POPs as a new focal area.
Global Mercury Assessment
This website supports the process to develop a global assessment of mercury and its compounds, including an outline of options for addressing any significant global adverse impacts of mercury.
Implementation of Strategic Approach to International Chemicals Management (SAICM)
The Governing Council of UNEP has requested the Executive Director, as a matter of high priority, to make appropriate provision for the implementation of UNEP’s responsibilities under SAICM and to make provision for activities to support developing countries and countries with economies in transition in implementing the strategic approach to international chemicals management, taking into account the Bali Strategic Plan for Technology Support and Capacity-building.
Lead and Cadmium Activities
UNEP is developing reviews of scientific information on lead and cadmium, focusing especially on long-range environmental transport, as requested by the UNEP Governing Council, in order to inform future discussions of the Governing Council on the possible need for global action in relation to these two heavy metals.
Partnership for Clean Fuels and Vehicles Clearing-house
UNEP is the clearing-house for the global Partnership for Clean Fuels and Vehicles, launched by World Summit partners in September 2002 at the World Summit on Sustainable Development.
Chemicals Information Exchange Network
The Chemical Information Exchange Network (CIEN) is a network of people involved in the management of chemicals.
Trade Names of Chemical Products Containing Ozone Depleting Substances and their Alternatives
The service Trade Names of Chemical Products containing ozone depleting substances and their alternatives is designed to help customs officials and National Ozone Units control imports and exports of ozone depleting substances (ODS) and prevent their illegal trade. It is a worldwide database of the commercial trade names of chemical products containing ODS controlled under the Montreal Protocol and their alternatives.
Global Programme of Action for the Protection of the Marine Environment from Land Based Activities (GPA)
The GPA aims at preventing the degradation of the marine environment from land-based activities by facilitating the duty of States to preserve and protect the marine environment.
This page provides access to health and safety information relating to the onshore chemical manufacture and storage industry.
This site relates to the following Industries: - Oil refining and petrochemicals; Paints and Coatings, Pharmaceuticals, Fertilisers, Compressed Gases and other general Chemicals.
The site does not cover the incidental use of chemicals in other places of work or the Offshore Oil and Gas Industry.
For information on Industries/Topics not covered here return to the HSE homepage.
The Chemical Industries Division has responsibility for the following industrial sectors:
Chemical production
Oil Refining and associated onshore oil-related industry
Coatings Production
Pharmaceuticals Production
Fertilisers Production
Production of Compressed Gases
Production of Hygiene/Cleaning materials
Large-scale storage of chemicals and their transport by road
These pages explain what we are doing to tackle key issues and provide access to a range of information about safety in the industry – for workers, employers and contractors. In fact, for anyone with an interest in health and safety with the Chemical Manufacture and Storage industries.

